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Oxycodone makes respiratory depression by means of immediate exercise at respiratory centers within the Mind stem and depresses the cough reflex by direct effect on the middle with the medulla.Oxycodone is contraindicated in any situation wherever opioids are contraindicated which include individuals with sizeable respiratory despair (in unmonitore

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Oxycodone generates respiratory depression via immediate activity at respiratory facilities within the brain stem and depresses the cough reflex by immediate effect on the center of your medulla.The combination of oxycodone and acetaminophen has not been evaluated for mutagenicity. Oxycodone alone was adverse in the bacterial reverse mutation assay

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